Publikationen

Capar, Ö., Tabatabai, M., Klee, J. E., Worm, M., Hartmann, L., & Ritter, H., “Fast curing of polyhydroxyurethanes via ring opening polyaddition of low viscosity cyclic carbonates and amines”. Polymer Chemistry, 2020, 11(43), 6964-6970. Link

Soria-Martinez, L.; Bauer, S.; Giesler, M.; Schelhaas, S.; Materlik, J.; Janus, K.; Pierzyna, P.; Becker, M.; Snyder, N. L.; Hartmann, L; Schelhaas, M, “Prophylactic Antiviral Activity of Sulfated Glycomimetic Oligomers and Polymers”. Journal of the American Chemical Society. 2020, 142, 5252-5265. Link

Freichel, T.; Heine, V.; Laaf, D.; Mackintosh, E. E.; Sarafova, S.; Elling, L.; Snyder, N. L.; Hartmann, L., “Sequence-Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin-3 and Delay Wound Healing of a Galectin-3 Positive Tumor Cell Line in an In Vitro Wound Scratch Assay”. Macromolecular Bioscience. 2020, 20, 202000163. Link

Hermann, A.; Hill, S.; Metz, A.; Heck, J.; Hoffmann, A.; Hartmann, L.; Herres-Pawlis, S.,  “Next Generation of Zinc Bisguanidine Polymerization Catalysts towards Highly Crystalline, Biodegradable Polyesters”. Angewandte Chemie. 2020, 123-41, 202008473. Link

Fischer, L.; Strzelczyk, A. K.; Wedler, N.; Kropf, C.; Schmidt, S.; Hartmann, L., ”Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion.” Chemical Science. 2020, 11, 9919-9924. Link

van der Meer, S. B.; Seiler, T.; Buchmann, C.; Partalidou, G.; Boden, S.; Loza, K.; Heggen, M.; Linders, J.; Prymak, O.; Oliveira, C. L. P.; Hartmann, L.; Epple, M., “Controlling the surface functionalization of ultrasmall gold nanoparticles by sequence-defined macromolecules.“ Chemistry – A European Journal. 2020, 26, 202003804. Link

Abd-El-Aziz, A. S.; Antonietti, M.; Barner-Kowollik, C.; Binder, W. H.; Böker, A.; Boyer, C.; Buchmeiser, M. R.; Cheng, S. Z. D.; D’Agosto, F.; Floudas, G.; Frey, H.; Galli, G.; Genzer, J.; Hartmann, L., et al.,  “The Next 100 Years of Polymer Science”. Macromolecular Chemistry and Physics. 2020, 221, 2000216. Link

Fischer, L.; Steffens, R.; Paul, T. J.; Hartmann, L., “Catechol-functionalized sequence-defined glycomacromolecules as covalent inhibitors of bacterial adhesion”. Polymer Chemistry. 2020, 37, 6091 – 6096. Link

Jacobi, F.; Wilms, D.; Seiler, T.; Queckbörner, T.; Tabatabai, M.; Hartmann, L.; Schmidt, S., “The effect of PEGylation on receptor anchoring and steric shielding at interfaces: an adhesion and surface plasmon resonance study with precision polymers”. Biomacromolecules. 2020, Just-Accepted Manuscript. Pub Date: September 28, 2020. Link

Bennion, M., Burch, M., Dennis, D., Lech, M., Neuhaus, K., Fendler, N., Parris, M., Cuadra, J., Dixon, C., Mukosera, G., Blauch, D., Hartmann, L., Snyder, N., Ruppel, J., "Synthesis of Porphyrin and Bacteriochlorin Glycoconjugates through CuAAC Reaction Tuning". European J Org Chem. 2019 17;2019(38):6496-6503. Link

Shamout, F.; Fischer, L.; Snyder, N. L.; Hartmann, L., "Recovery, Purification, and Reusability of Building Blocks for Solid Phase Synthesis". Macromolecular Rapid Communications. 2019, 1900473. Link

Shamout, F.; Monaco, A.; Yilmaz, G.; Becer, C. R.; Hartmann, L., "Synthesis of Brush‐Like Glycopolymers with Monodisperse, Sequence‐Defined Side Chains and Their Interactions with Plant and Animal Lectins". Macromolecular rapid communications. 2019, 1900459. Link

Neuhaus, K.; Wamhoff, E. C.; Freichel, T.; Grafmüller, A.; Rademacher, C.; Hartmann, L., "Asymmetrically Branched Precision Glycooligomers Targeting Langerin". Biomacromolecules. 2019, 20, 4088-4095. Link

Camaleño de la Calle, A.; Gerke, C.; Chang, X. J.; Grafmüller, A.; Hartmann, L.; Schmidt, S., "Multivalent Interactions of Polyamide Based Sequence‐Controlled Glycomacromolecules with Concanavalin A". Macromolecular bioscience. 2019, 19, 1900033. Link

Baier, M.; Rustmeier, N. H.; Harr, J.; Cyrus, N.; Reiss, G. J.; Grafmüller, A.; Blaum, B. S.; Stehle, T.; Hartmann, L., "Divalent Sialylated Precision Glycooligomers Binding to Polyomaviruses and the Effect of Different Linkers". Macromolecular Bioscience. 2019, 19, 1800426. Link

Bücher, K. S.; Konietzny, P. B.; Snyder, N. L.; Hartmann, L., "Heteromultivalent Glycooligomers as Mimetics of Blood Group Antigens". Chemistry – A European Journal. 2019, 25, 1 -10. Link

Boden, S.; Reise, F.; Kania, J.; Lindhorst, T. K.; Hartmann, L., "Sequence-Defined Introduction of Hydrophobic Motifs and Effects in Lectin Binding of Precision Glycomacromolecules". Macromolecular Bioscience. 2019, 1800425. Link

Gerke, C.; Siegfeld, P.; Schaper, K.; Hartmann, L., "Enabling Directional Sequence-Control via Step-Growth Polymerization of Heterofunctionalized Precision Macromonomers". Macromolecular Rapid Communications. 2019, 40, 1800735. Link

Freichel, T.; Laaf, D.; Hoffmann, M.;Konietzny, P. B.; Heine, V.; Wawrinek, R.; Rademacher, C.; Snyder, N. L.; Elling, L.; Harmann, L. "Effects of linker and liposome anchoring on lactose-functionalized glycomacromolecules as multivalent ligands for binding galectin-3". RSC Advances. 2019, 23484-23497. Link

Baier, M.; Ruppertz, J. L.; Pfleiderer, M. M.; Blaum, B. S.; Hartmann, L., Synthesis of highly controlled carbohydrate–polymer based hybrid structures by combining heparin fragments and sialic acid derivatives, and solid phase polymer synthesis. Chemical Communications. 2018, 54, 10487-10490. Link

Bücher, K. S.; Yan, H.; Creutznacher, R.; Ruoff, K.; Mallagaray, A.; Grafmüller, A.; Dirks, J. S.; Kilic, T.; Weickert, S.; Rubailo, A.; Drescher, M.; Schmidt, S.; Hansman, G.; Peters, T.; Uetrecht, C.; Hartmann, L., Fucose-Functionalized Precision Glycomacromolecules Targeting Human Norovirus Capsid Protein. Biomacromolecules. 2018, 19, 3714-3724. Link

Jacobi, F.; Camaleño de la Calle, A.; Boden, S.; Grafmüller, A.; Hartmann, L.; Schmidt, S., Multivalent Binding of Precision Glycooligomers on Soft Glycocalyx Mimicking Hydrogels. Biomacromolecules. 2018, 19, 3479-3488. Link

Gerke, C.; Jacobi, F.; Goodwin, L. E.; Pieper, F.; Schmidt, S.; Hartmann, L., Sequence-Controlled High Molecular Weight Glyco(oligoamide)–PEG Multiblock Copolymers as Ligands and Inhibitors in Lectin Binding. Macromolecules. 2018, 51, 5608-5619. Link

Pasch, P.; Papadopoulos, J.; Goralczyk, A.; Hofer, M. L.; Tabatabai, M.; Müller, T. J. J.; Hartmann, L., Highly Fluorescent Merocyanine and Cyanine PMMA Copolymers, Macromolecular Rapid Communications. 2018, 39, 1800277. Link

Hill, S. A.; Gerke, C.; Hart­mann, L., "Re­cent De­vel­op­ments in Solid-​Phase Strate­gies to­wards Syn­thetic, Sequence-​Defined Macro­mol­e­cules". Chem­istry – An Asian Jour­nal. 2018, 13, 3611-​3622. Link

Bücher, K. S.; Babic, N.; Fre­ichel, T.; Ko­vacic, F.; Hart­mann, L., "Monodis­perse Sequence-​Controlled α-​l-Fucosylated Gly­cooligomers and Their Mul­ti­va­lent In­hibitory Ef­fects on LecB". Macro­mol­e­c­u­lar Bio­science. 2018, 18, 1800337. Link

Stehle, T.; Pe­ters, T.; Hart­mann, L.; Schel­haas, M., Gly­cans Con­trol­ling Virus In­fec­tions: Meet­ing Re­port on the 1st In­ter­na­tional Sym­po­sium on Gly­covi­rol­ogy Schöntal, Ger­many, 02–04 May 2018. Viruses 2018, 10(11), 636. Link

M. Baier, M. Giessler, L. Hartmann, Split & Combine Approach towards Branched Precision Glycomacromolecules and their Lectin Binding Behavior, Chemistry – A European Journal, 2018, 24(7), 1619-1630. Link

S. Boden, K. Wagner, M. Karg, L. Hartmann, Presenting Precision Glycomacromolecules on Gold Nanoparticles for Increased Lectin Binding, Polymers, 2017, 9 (12), 716 Link

M.F. Ebbesen, D. Itskalov,  M. Baier, L. Hartmann, Cu Elimination from Cu-Coordinating Macromolecules, ACS Macro Letters, 2017, 6, 399-403. Link

C. Gerke,  M.F. Ebbesen, D. Jansen, S. Boden,  T. Freichel, L. Hartmann,  Sequence-Controlled Glycopolymers via Step-Growth Polymerization of Precision Glycomacromolecules for Lectin Receptor Clustering, Biomacromolecules, 2017, 18, 787-796. Link

H. Wang, F. Jacobi, J. Waschke, L. Hartmann,  H. Löwen, S. Schmidt,  Elastic Modulus Dependence on the Specific Adhesion of Hydrogels, Advanced Functional Materials, 2017, 27, 1702040-n/a. Link

T. Freichel,S. Eierhoff, N.L. Snyder, L. Hartmann, Toward Orthogonal Preparation of Sequence-Defined Monodisperse Heteromultivalent Glycomacromolecules on Solid Support Using Staudinger Ligation and Copper-Catalyzed Click Reactions, The Journal of Organic Chemistry, 2017, 82, 9400-9409. Link

S. Igde, S. Röblitz, A. Müller, K. Kolbe, S. Boden, C. Fessele, T.K. Lindhorst, M. Weber, L. Hartmann, Linear Precision Glycomacromolecules with Varying Interligand Spacing and Linker Functionalities Binding to Concanavalin A and the Bacterial Lectin FimH, Macromolecular Bioscience, 2017, 12, 1700198-n/a. Link

I. Joachim, S. Rikker, D. Hauck, D. Pon­ader, S. Boden, R. Som­mer, L. Hart­mann, A. Titz, De­vel­op­ment and op­ti­miza­tion of a com­pet­i­tive bind­ing assay for the galac­tophilic low affin­ity lectin LecA from Pseudomonas aerug­i­nosa, Or­ganic & Bio­mol­e­c­u­lar Chem­istry, 2016, 14, 7933-​7948. Link

P.M. Klein, S. Reinhard, D.-J. Lee, K. Müller, D. Ponader, L. Hartmann, E. Wagner, E, Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes,  Nanoscale, 2016, 8, 18098-18104. Link

M.F. Ebbesen, C. Gerke, P. Hartwig, L. Hartman, Biodegradable poly(amidoamine)s with uniform degradation fragment via sequence-controlled macromonomers, Polymer Chemistry, 2016, 7,  7086-7093. Link

Laura Hart­mann was guest ed­i­tor for Macro­mol­e­c­u­lar Chem­istry and Physics for two spe­cial is­sues invit­ing the ‘Young Tal­ents’ in these fields:

"Young Talents in Polymer Science" Link

"Rising Stars in Polymer Science" Link

M.F. Broecker, J. Hanske, C.E. Mar­tin, J.Y. Baek, A. Wahlbrink, F. Wo­j­cik, L. Hart­mann, C. Rademacher, C. Anish, P.H. See­berger, Mul­ti­va­lent dis­play of min­i­mal Clostrid­ium dif­fi­cile gly­can epi­topes mim­ics anti­genic prop­er­ties of larger gly­cans, Nat Com­mun, 2016, 7, 11224 Link

K. En­g­berg, D.J. Wa­ters, S. Kel­manovich, R. Parke-​Houben, L. Hart­mann, M.F.Toney, C.W. Frank, Self-​assembly of cho­les­terol teth­ered within hy­dro­gel net­works, Poly­mer, 2016, 84, 371-​382. Link

S. Schimka, S.A. San­ter, N.M. Mujkic-​Ninnemann, D. Bleger, L. Hart­mann, M. Wehle, R. Lipowsky, M. San­ter, Pho­to­sen­si­tive pep­tidomimetic for light con­trolled re­versible DNA com­paction,  Bio­macro­mol­e­cules, 2016, 17, 1959–1968. Link

Laura Hart­mann and C. Remzi Becer edited a book on the role of sug­ars in poly­mer and ma­te­r­ial sci­ences called ‚The Gly­cocode‘ Link

 U.I.M Gerling-​Driessen, N. Mujkic-​Ninnemann, D. Pon­ader, D. Schöne, L. Hart­mann and B. Koksch, Ex­ploit­ing the oligo(amido amine) back­bones for the mul­ti­va­lent pre­sen­ta­tion of coiled coil pep­tides, Bio­macro­mol­e­cules, 2015, 16 (8), 2394–2402. Link

S. Schmidt, H. Wang, D. Pussak, S. Mosca, L. Hartmann, Probing multivalency in ligand–receptor-mediated adhesion of soft, biomimetic interfaces, Beilstein J. Org. Chem. 2015, 11, 720-729. Link

S. Mar­tin, H. Wang, L. Hart­mann, T. Pompe and S. Schmidt, Quan­tifi­ca­tion of protein-​materials in­ter­ac­tions by soft col­loidal probe spec­troscopy, Phys. Chem. Chem. Phys., 2015, 17, 3014-​3018. Link

S. Wieczorek, S. Vigne, T. Masini, D. Ponader, L. Hartmann, A.K.H. Hirsch, H.G. Börner, Combinatorial Screening for Specific Drug Solubilizers with Switchable Release Profiles, Macromol. Chem. Phys. 2015, 15(1), 82-89. Link

D. Pussak, D. Ponader, S. Mosca, T. Pompe, L. Hartmann, S. Schmidt, Specific adhesion of carbohydrate hydrogel particles in competition with multivalent inhibitors evaluated by AFM, Langmuir, 2014, 30(21), 6142-6150. Link

D. Ponader, S. Igde, M. Wehle, K. Märker, M. Santer, D. Bléger and L. Hartmann, Photoswitchable precision glycooligomers and their lectin binding, Beilstein J. Org. Chem., 2014, 10, 1603–1612. Link

M. Glaubitz, N. Medvedev, D. Pussak, L. Hartmann, S. Schmidt, C.A. Helm, M. Delcea, A novel contact model for AFM indentation experiments on soft spherical cell-like particles, Soft Matter, 2014, 10 (35), 6732-6741. Link

D. Dechtrirat, N. Gajovic-Eichelmann, F. Wojcik, L. Hartmann, F.F. Bier, F.W. Scheller, Electrochemical displacement sensor based on ferrocene boronic acid tracer and immobilized glycan for saccharide binding proteins and E. coli, Biosensors & Bioelectronics, 2014, 58, 1-8. Link

D. Ponader, P. Maffre, J. Aretz, D. Pussak, N.M. Ninnemann, S. Schmidt, P. H. Seeberger, C. Rademacher, G. U. Nienhaus, L. Hartmann, Carbohydrate-Lectin Recognition of Sequence-Defined Heteromultivalent Glycooligomers J.Am.Chem.Soc., 2014, 136, 2008−2016. Link

S. Mosca, J. Keller, N. Azzouz, S. Wagner, A. Titz, P. H. Seeberger, G. Brezesinski, and L. Hartmann, Amphiphilic Cationic β^3R3-Peptides: Membrane Active Peptidomimetics and Their Potential as Antimicrobial Agents Biomacromolecules, 2014, 15 (5), 1687–1695 Link

S. Schmidt, A. Reinecke, F. Wojcik, D. Pussak, L. Hartmann, and M. J. Harrington, Metal-mediated molecular self-healing in histidine-rich mussel peptides Biomacromolecules, 2014, 15 (5), 1644–1652 Link

M. Behra, L. Hartmann, Ammonium Carbamate Functionalization of Microgels for pH-Sensitive Loading and Release of Anionic and Cationic Molecules, Macromol. Chem. Phys., 2014, 215 (1), 90-95. Link

S. Schmidt, M. Behra, K. Uhlig, N. Madabossi, L. Hartmann, C. Duschl, D. Volodkin, Mesoporous Protein Particles through Colloidal CaCO3 Templates, Advanced Functional Materials 2013, 23, 116-123. Link

S. Mosca, C. Dannehl, U. Möginger, G. Brezesinski, , L. Hartmann, β3R3-Peptides: design and synthesis of novel peptidomimetics and their self-assembling properties at the air–water interface, Organic & Biomolecular Chemistry 2013, 11(33), 5399-5403. Link

F. Wojcik,S. Lel,A. G. O’Brien, P. H. Seeberger and L. Hartmann, Synthesis of Homo- and Heteromultivalent Carbohydrate-Functionalized Oligo(amidoamines) Using Novel Glyco-Building Blocks, Beilstein Journal of Organic Chemistry 2013, 9, 2395–2403. Link

M. Behra, L. Hartmann, L. Ammonium-carbamate functionalization of microgels for pH-sensitive loading and release of anionic and cationic molecules, Macromolecular Chemistry and Physics 2013. Link

D. Pussak, D. Ponader, S. Mosca, S. Vargas Ruiz, L. Hartmann and S. Schmidt, Mechanical Carbohydrate Sensors based on Soft Hydrogel Particles, Angewandte Chemie International Edition 2013, 52, 6084-6087. Link

M. Behra, N. Azzouz, S. Mosca, M. Chanana, P. H. Seeberger, L. Hartmann, Magnetic Porous Sugar-Functionalized PEG Microgels for Efficient Isolation and Removal of Bacteria from Solution, Biomacromolecules 2013, 14, 1927-1935. Link

X. W. Tan, L. Hartmann, K. P. Tan, R. Poh, L. L. Zheng, D. Dale Waters, D. Myung, J. Noolandi, R. W. Beuerman, C. W. Frank, C. N. Ta, D. Tan, J. S. Mehta, In vivo biocompatibility of two PEG/PAA interpenetrating polymer networks as corneal inlays following deep stromal pocket implantation, Journal of Materials Science: Materials in Medicine, 2013, 24, 967–977. Link

K. Stavenhagen, H. Hinneburg, M. Thaysen-Andersen, L. Hartmann, D. Varón Silva, J. Fuchser, S. Kaspar, E. Rapp, P. H. Seeberger, D. Kolarich, Quantitative Mapping of Glycoprotein Micro- and Macroheterogeneity: An Evaulation of Mass Spectrometry Signal and Strengths Using Synthetic Peptides and Glycopeptides,  Journal of Mass Spectrometry 2013, 48, 627-639. Link

F. Wojcik, A. G. O'Brien, S. Götze, P. H. Seeberger and L. Hartmann, Synthesis of Carbohydrate-Functionalised Sequence-Defined Oligo(amidoamine)s by Photochemical Thiol-Ene Coupling in a Continous Flow Reactor, Chemistry-A European Journal 2013, 19, 3090-3098. Link

S. Schmidt, M. Behra, K. Uhlig, N. Madabossi, L. Hartmann, Mesoporous Protein Particles through Colloidal CaCO3 Templates, Advanced Functional Materials 2013, 23, 116-123. Link

D.Ponader, F. Wojcik, F. Beceren-Braun, J. Dernedde, L. Hartmann, Sequence-Defined Glycopolymer Segments Presenting Mannose: Synthesis and Lectin Binding Affinity, Biomacromolecules 2012, 13, 1845-1852. Link

F. Wo­j­cik, S. Mosca, L. Hart­mann, Solid-​Phase Syn­the­sis of Asym­met­ri­cally Branched Sequence-​Defined Poly/Oligo(ami­doamines) , Jour­nal of Or­ganic Chem­istry 2012, 77, 4226-​4234. Link

M.Behra, S. Schmidt, J. Hartmann, D. V. Volodkin, L. Hartmann, Synthesis of Porous PEG Microgels Using CaCO₃ Microspheres as Hard Templates, Macromolecular Rapid Communications 2012, 33, 1049-1054. Link

L. Hart­mann, K. Watan­abe, L. Zheng, C. Kim, S. Beck, P. Huie, J. Noolandi, J. Cochran, C. N. Ta, C. W. Frank, To­wards the De­vel­op­ment of an Ar­ti­fi­cial Cornea: Im­proved Sta­bil­ity of In­ter­pen­e­trat­ing Poly­mer Net­works., Jour­nal of Bio­med­ical Ma­te­r­ial Re­search Part B 2011, 98, 8-17. Link

L. Hartmann, Polymers for Control Freaks: Sequence-Defined Poly(amidoamine)s and Their Biomedical Applications, Macromolecular Chemistry and Physics 2011, 212, 8–13. Link

S. Mosca, F. Wojcik, L. Hartmann, Precise Positioning of Chiral Building Blocks in Monodisperse, Sequence-Defined Polyamides, Macromolecular Rapid Communications 2011, 32, 197–202. Link

D. Pussak, M. Behra, S. Schmidt, L. Hartmann, Synthesis and functionalization of poly(ethylene glycol) microparticles as soft colloidal probes for adhesion energy measurements, Soft Matter 2011, 8, 1664-1672. Link

D. J. Waters, K. Engberg, R. Parke-Houben, L. Hartmann, C. N. Ta, M. F. Toney, C. W. Frank, Morphology of Photopolymerized End-Linked Poly(ethylene glycol) Hydrogels by Small-Angle X-ray Scattering, Macromolecules 2010, 43, 6861-6870. Link

Hartmann, L.; Bedard, M.; Börner, H. G.; Möhwald, H.; Sukhorukov, G. B.; Antonietti, M., CO2-switchable oligoamine patches based on amino acids and their use to build polyelectrolyte containers with intelligent gating, Soft Matter 2008, 4, 534-549.

L. Hartmann, S. Häfele, R. Peschka-Süss, M. Antonietti, H.G. Börner, Tailor-Made Poly(amidoamine)s for Controlled Complexation and Condensation of DNA, Chemistry European Journal 2008, 14, 2025. Link

L. Hartmann, S. Häfele, R. Peschka-Süss, M. Antonietti, H.G. Börner, Sequence Positioning of Disulfide Linkages to Program the Degradation of Monodisperse Poly(amidoamines), Macromolecules 2007, 40, 7771. Link

Hartmann, L.; Haefele, S.; Antonietti, M.; Boerner, H. G. Tailor-made poly(amidoamines) for biomedical application, PMSE Preprints 2006, 95, 790-791.

Hartmann L., Krause E., Antonietti M., H. G. Börner, Solid-Phase Supported Polymer Synthesis of Sequence-Defined, Multifunctional Poly(amidoamines), Biomacromolecules, 2006, 7, 1239. Link

Tiller, J. C.; Hartmann, L.; Scherble, J., Reloadable antimicrobial coatings based on amphiphilic silicone networks, Surface Coatings International, Part B: Coatings Transactions 2005, 88(B1), 49-53. Link

Tiller, J. C.; Sprich, C.; Hartmann, L., Amphiphilic conetworks as regenerative controlled releasing antimicrobial coatings, Journal of Controlled Release 2005, 103(2), 355-367. Link

Bruns, N.; Scherble, J.; Hart­mann, L.; Thomann, R.; Ivan, B.; Muel­haupt, R.; Tiller, J. C., Nanophase Sep­a­rated Am­phiphilic Conet­work Coat­ings and Mem­branes.  Macromolecules 2005, 38(6), 2431-2438. Link